Full Article: PDF
Scientific Object Identifier: http://s-o-i.org/1.1/TAS-11-43-8
DOI: http://dx.doi.org/10.15863/TAS.2016.11.43.8
Language: Russian
Citation: Salekhov SA, Salekhova MP, Maksimyuk NN (2016) ADAPTATION VALUES OF TYPE 2 DIABETES IN LONG PSYCHOLOGICAL STRESS. ISJ Theoretical & Applied Science, 11 (43): 37-40. Soi: http://s-o-i.org/1.1/TAS-11-43-8 Doi: http://dx.doi.org/10.15863/TAS.2016.11.43.8 |
Pages: 37-40
Published: 30.11.2016
Abstract: From the standpoint of the dominant AA Ukhtomskii theory of functional systems PK Anokhin, principles endogenization pathological process, psycho-emotional information-energy theory of obesity and increasing needs of the central nervous system of glucose and kisloroe on the background of the prolonged psychological stress justified the development of insulin resistance as a compensatory-adaptive response to ensure the normal function of the central nervous system on the background of insulin resistance as an alternative energy amino acids are preferably used a substrate, which leads to violation of their scarcity and ornithine cycle protein synthesis in the liver. Reduction of protein synthesis leads to a decrease in blood oncotic pressure, its thickening, disruption of the microcirculation and the transition to the anaerobic catabolism. Violation microcirculation and anaerobic catabolism in the central nervous system leads to energy deficit, offset by hyperglycemia. That is, type 2 diabetes is an adaptive response of the body with long-term psychological stress.
Key words: Type 2 diabetes, psychological stress, adaptation, insulin resistance, hyperglycemia, anaerobic catabolism.
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