Full Article: PDF
Scientific Object Identifier: http://s-o-i.org/1.1/TAS-09-65-24
DOI: https://dx.doi.org/10.15863/TAS.2018.09.65.24
Language: English
Citation: Noor S, Iftikhar N, Sabahat A (2018) MORBIDITY AND MORTALITY ASSOCIATED WITH SPONTANEOUS BACTERIAL PEROTONITIS. ISJ Theoretical & Applied Science, 09 (65): 149-153. Soi: http://s-o-i.org/1.1/TAS-09-65-24 Doi: https://dx.doi.org/10.15863/TAS.2018.09.65.24 |
Pages: 149-153
Published: 30.09.2018
Abstract: Objective: To find out consequences of spontaneous bacterial peritonitis and its causative organisms and to determine sensitivity of these organisms for antibiotics. Design and Duration: This is an observational descriptive study completed in duration of 8 months from October 2017 to May 2018. Setting: This study was conducted in Khyber teaching Hospital Peshawar Pakistan. Patients and Methods: All The cases presented in emergency ward of the hospital with spontaneous bacterial peritonitis with ascites due to liver cirrhosis, during the study period were selected for study. An inclusion criterion was developed for selecting patients for the study according to that patients with SBP directly presented to the hospital first time for this disease, having no other infective disease other than, having ascites due to liver cirrhosis only, No other cause of ascites, no history of trauma or invasive abdominal procedure leading to peritonitis. Patients from both male and female populations were included in this study. Under aseptic measures ascetic tap done using 10 ml syringe and ascitic fluid sent for examination and culture sensitivity determined for isolated organisms. All cases in study group were admitted in the surgical ward and empirical management was given before culture report came. After culture report antibiotic was given accordingly. Written consent was taken from all study cases and also from the medical superintendant of the hospital. Data was analyzed in SPSS and Microsoft office version 2018. Results: There were total 90 cases in this study having ascites due to liver cirrhosis and signs and symptoms of peritonitis. Age range of these cases was 32-74 years with mean age of 48±15.5 years. Most of the cases were having age above 45 years. There were 55.6% male and 44.4% female cases. Ascitic fluid culture was positive in 47.8% and negative in 52.2% cases. Out of total cases with positive culture growth 55.8% showed gram negative bacteria, 30.2% gram positive and in 14% cases other organisms were isolated. In 43 culture positive cases 39.5% showed E.coli, 25.6% streptococcus pneumonia, In 11.6% Klebsiella, in 9.3% staphylococcus aureus and in 13.9% cases other organisms were isolated. Confidence level was 95% with P-value less than 0.05. Conclusion: Gram negative organisms are most common cause of spontaneous bacterial peritonitis in liver cirrhotic patients. E-coli is most common gram negative bacteria responsible for it. It is associated with high morbidity and mortality rate.
Key words: Spontaneous bacterial peritonitis, Liver cirrhosis, Ascitic fluid examination.
|
