Full Article: PDF
Scientific Object Identifier: http://s-o-i.org/1.1/TAS-09-65-44
DOI: https://dx.doi.org/10.15863/TAS.2018.09.65.44
Language: Russian
Citation: Khalilova VZ, Efedyev AM, Jafarova GA, Gasimov NV (2018) CHANGE IN SOME BIOCHEMICAL INDICATORS IN WOMEN WITH ONCOLOGICAL DISEASES OF THE REPRODUCTIVE SYSTEM. ISJ Theoretical & Applied Science, 09 (65): 264-268. Soi: http://s-o-i.org/1.1/TAS-09-65-44 Doi: https://dx.doi.org/10.15863/TAS.2018.09.65.44 |
Pages: 264-268
Published: 30.09.2018
Abstract: This study included 47 patients. All the examined patients were divided into three groups: 1) group - benign neoplasms (23); 2) group - malignant tumors (15); 3) group - metastatic tumors. 15 healthy people were included in the control group. The concentration of CA125 in the group of women with cancer of the female reproductive system was significantly increased (205.1 ± 16.83 ng / ml) in comparison with the group of practically healthy people (12.8 ± 0.06 ng / ml). The data obtained suggest that the increase in CA125 in the serum of patients with malignant tumors is important in assessing the aggressiveness of the process. In patients with malignant tumors, there was a significant increase in IL-8 and TNF-?, as well as the activity of ALP, ALT, ACT, GGT in the serum compared to benign tumors with metastases. The data presented by us indicate that CA125, IL-8, TNF-? and ALP activity are closely related to the pathogenic mechanisms of malignant tumor growth.
Key words: cancer of the reproductive system of women, CEA, CA125, inteleikin-8, tumor necrosis factor, alkaline phosphatase.
|
