ISJ Theoretical & Applied Science 10(114) 2022

Philadelphia, USA

Elyasov, M. A., Khojakuliyev, B. G., & Jumaev, Kh.

Humoral factors of inflammatory response in patients with type 2 diabetes mellitus, after endovascular revascularization.

Full Article: PDF

Scientific Object Identifier: http://s-o-i.org/1.1/TAS-10-114-42

DOI: https://dx.doi.org/10.15863/TAS.2022.10.114.42

Language: Russian

Citation: Elyasov, M. A., Khojakuliyev, B. G., & Jumaev, Kh. (2022). Humoral factors of inflammatory response in patients with type 2 diabetes mellitus, after endovascular revascularization. ISJ Theoretical & Applied Science, 10 (114), 286-291. Soi: http://s-o-i.org/1.1/TAS-10-114-42 Doi: https://dx.doi.org/10.15863/TAS.2022.10.114.42

Pages: 286-291

Published: 30.10.2022

Abstract: Atherosclerosis is considered as an inflammatory process in the arterial wall, the course of which consists of alternating periods of long remissions. Active attempts are being made to suppress leukocyte migration after coronary stenting by blocking certain chemokines that are key to this process. The dynamics of proinflammatory markers in the blood after implantation of sirolimus-containing coronary stents in patients with coronary artery disease with type 2 diabetes has been studied. Summarizing the data obtained, the increase in CRP and IL 6 was due to an early inflammatory response to stenting within 3 days after the procedure, which was subsequently replaced by a longer phase of lowering the concentration of inflammatory markers in the blood. The level of CRP in the groups did not reach the reference values. At the same time, there were differences in the rate of decrease in the concentration of CRP after the initial increase caused by the procedure.

Key words: diabetes, atherosclerosis, coronary heart disease, CRP.