Mamedova, U.F., Hasanova, S.I., Rustamova, A.A., & Amraliev, N.M.
The study of the informativeness and diagnostic value of some cytokines and antimicrobial peptides in thyroid cancer. |
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Full Article: PDF
Scientific Object Identifier: http://s-o-i.org/1.1/TAS-10-66-35
DOI: https://dx.doi.org/10.15863/TAS.2018.10.66.35
Language: Russian
Citation: Mamedova, U.F., Hasanova, S.I., Rustamova, A.A., & Amraliev, N.M. (2018). The study of the informativeness and diagnostic value of some cytokines and antimicrobial peptides in thyroid cancer. ISJ Theoretical & Applied Science, 10 (66), 301-306. Soi: http://s-o-i.org/1.1/TAS-10-66-35 Doi: https://dx.doi.org/10.15863/TAS.2018.10.66.35 |
Pages: 301-306
Published: 30.10.2018
Abstract: In this work, were analyzed the information content and diagnostic significance of some cytokines and antimicrobial peptides (AMP) were analyzed using ROC analysis. For this purpose, the levels of IL-6, ?-TNF, calprotectin, lactoferrin, defensin and L-FABP were examined by enzyme immunoassay in the serum of patients with thyroid cancer and thyroid adenoma (ASH). As a result of the study in patients with thyroid cancer, a significant increase in the content of IL-6, ?-TNF, calprotectin, lactoferrin and defensin was found in comparison with patients with ASH. The highest elevated values were observed in patients with the follicular form of thyroid cancer. Using ROC analysis, it was established that IL-6, TNF ? and TNT, calprotectin, lactoferrin and defensin have diagnostic value for the early detection of process malignancy.
Key words: thyroid cancer, thyroid adenoma, interleukin-6, tumor necrosis factor, antimicrobial peptides
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