ISJ Theoretical & Applied Science 03(83) 2020

Philadelphia, USA

Kurbanova, M. M., Asadov, K. A., Huseyinov, E. Z., Safarova, A. S., & Abdullaeva, F. M.

The Synthesis of optically active methyl 2,7,7-trimethyl-5-oxo-4- (4-methoxyphenyl) -1,4,5,6,7,8-hexahydroxynolin-3-carboxylate based on modified Hans reaction.

Full Article: PDF

Scientific Object Identifier: http://s-o-i.org/1.1/TAS-03-83-34

DOI: https://dx.doi.org/10.15863/TAS.2020.03.83.34

Language: English

Citation: Kurbanova, M. M., Asadov, K. A., Huseyinov, E. Z., Safarova, A. S., & Abdullaeva, F. M. (2020). The Synthesis of optically active methyl 2,7,7-trimethyl-5-oxo-4- (4-methoxyphenyl) -1,4,5,6,7,8-hexahydroxynolin-3-carboxylate based on modified Hans reaction. ISJ Theoretical & Applied Science, 03 (83), 160-164. Soi: http://s-o-i.org/1.1/TAS-03-83-34 Doi: https://dx.doi.org/10.15863/TAS.2020.03.83.34

Pages: 160-164

Published: 30.03.2020

Abstract: On the basis modified Hans reaction and with the presence of various catalysts has been synthesized optically active methyl 2,7,7-trimethyl-5-oxo-4- (4-methoxyphenyl) -1,4,5,6,7,8-hexahydroxinoline-3- carboxylate. The degree of optical purity of the synthesized compound was studied by HPLC analysis. Factors influencing to the practical output of the reaction and the degree of optical purity of the synthesized compound were studied in comparative form in two- and three-component reactions.

Key words: Assimetric Hans reaction, chiral catalyst, optical purity degree.