Full Article: PDF
Scientific Object Identifier: http://s-o-i.org/1.1/TAS-10-102-94
DOI: https://dx.doi.org/10.15863/TAS.2021.10.102.94
Language: Russian
Citation: Dzhuraev, Zh. A., & Mukhiddinov, A. I. (2021). COVID-19 and nasal conditions. ISJ Theoretical & Applied Science, 10 (102), 837-841. Soi: http://s-o-i.org/1.1/TAS-10-102-94 Doi: https://dx.doi.org/10.15863/TAS.2021.10.102.94 |
Pages: 837-841
Published: 30.10.2021
Abstract: The nasal epithelium expressing enriched angiotensin-converting enzyme II (ACE2), a key receptor for the penetration of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) into cells, can serve as the first barrier to protect the respiratory tract from viral infection. Recent studies have shown that patients with coronavirus disease 2019 (COVID-19) have been found to have a higher viral load in the nasal cavity than in the pharynx, and otolaryngologists should carefully consider infection prevention in clinical practice for the treatment of nasal conditions. Moreover, several studies have shown that anosmia is one of the clinical characteristics of COVID-19, but the exact prevalence and mechanism remain unclear. So far, the concomitant pathology of allergic rhinitis and chronic rhinosinusitis is not the main risk factor for severe COVID-19. However, we need to develop strategies in clinical practice for the treatment of nasal diseases during a pandemic. In this article, we reviewed the current evidence of a link between COVID-19 and nasal conditions such as olfactory dysfunction associated with COVID-19, allergic reactions, rhinitis and chronic rhinosinusitis.
Key words: coronavirus infection, nasal cavity, chronic rhinitis, epithelium.
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